Introduction: The topic of publication ethics is increasingly important in scientific discussions, especially the issues of accurate and honest representation of author contributions in the creation of scientific articles.

Description of the CREDIT System: The contribution to authorship of an article is determined not only by participation in writing the text but also by the overall contribution of the participant in conducting the research itself. The CREDIT authorship model allows for precise tracking of each participant's contribution to the research project, describing various author roles, some of which may be independent, while others complement more significant roles.

Conclusion: Detailed coverage of the CREDIT taxonomy and the procedure for documenting author contribution enhances the transparency of scientific communication.

Introduction: Lactic acid microorganisms have valuable biotechnological and probiotic properties. Probiotic properties are often mediated by biologically active metabolites produced by these microorganisms. The ability of lactic acid microorganisms to produce biologically active compounds has received special attention in recent years, as their positive effect on the human body has been determined. However, there is a huge knowledge gap regarding the composition of metabolite complexes that requires study to ensure their safe use.

Purpose: The current study of the metabolite complex produced by L. reuteri LR1, obtained by cultivating the strain in the MRS broth nutrient medium at a temperature of (37±1)ºС for 24 hours.

Materials and Methods: The object of research was a cell-free supernatant (metabolite complex) obtained by cultivating the Lactobacillus reuteri LR1 strain from the collection of the Federal State Scientific Institution “VNIMI”. The antimicrobial activity of MK L. reuteri LR1 against E. coli ATCC 25922, S. aureus ATCC 6538, S. typhimurium ATCC 14028 was determined by the agar diffusion method. The antioxidant activity of the samples was determined using the ORAC fluorescence method. The content of organic and amino acids in LA was determined by capillary electrophoresis. Identification of secondary metabolites present in MK was carried out using gas chromatography-mass spectrometry (GC-MS).

Results: The biological activity of MK produced by L. reuteri LR1 was determined. The composition of the cell-free metabolite complex secreted by L.reuteri LR1 during cultivation in the MRS broth nutrient medium at a temperature of 37°C for 24 hours was characterized. The presence of amino acids and organic acids in LA was confirmed and their content was determined. In addition, secondary metabolites present in MK have been identified, some of them have confirmed biological activity.

Conclusion: The results obtained may be useful for predicting the probiotic potential of MK, however, it is necessary to determine the likely correlation between the composition of MK and its beneficial properties, which will allow us to identify new possibilities for the use of MK produced by probiotic microorganisms.

Background: The use of ozone allows not only to weaken the connection of moisture with the grain, but also, interacting with its internal components, the gas contributes to an increase in the temperature of the heap. Due to this, the grain must be heated for less time before reaching optimal parameters, which reduces the energy intensity of the drying process. At the same time, the separation of moisture from the grain occurs more intensively, since the gas in small concentrations improves the permeability of cell membranes, causes structural transformations of the integumentary tissues and promotes the orientation of water molecules around atomic oxygen. As a result, the drying time is significantly reduced. After treatment, the residual ozone decays to oxygen without polluting the environment. In addition, ozonation promotes deodorization, sanitation, sterilization of grain and equipment. However, the use of ozone-air mixture in grain drying in production is too insignificant due to the small experimental base and lack of practical recommendations.

Purpose: Improving the efficiency of modern grain dryers through the use of the ozonation process.

Materials and Мethods: The theoretical and methodological basis of the research was the work in the field of grain drying with an ozone-air mixture by leading Russian and foreign scientists, as well as their own research. The sources under study cover the first mentions of the use of ozone in grain drying and the subsequent development of this topic. The review included publications from various databases, among which are: e-library, Scopus, Web of Science, Agris, FIPS and others.

Results: Hourly preliminary ozonation of grain with a humidity of 26.3% contributed to a decrease in the moisture content by 1.3% from the initial value. While in the control sample, which was not subjected to preliminary ozone treatment, the moisture content did not change over the same period. Subsequent drying of the exposed grain allowed for an hour of operation to remove 1.6% more moisture than that of the control sample. At the same time, the drying conditions of both batches of grain were identical. This indicates that the ventilation of grain with an ozone-air mixture is more effective than its presence in a buffer silo without processing.

Conclusion: Pretreatment of a wet grain heap with an ozone-air mixture before feeding it to the grain dryer intensifies the process of subsequent grain drying. At the initial grain moisture content of 26.3%, hourly ozone treatment with an ozone concentration in an ozone-air mixture of 8 mg/m3 reduces the moisture content by 5.4% per hour of drying. Under the same conditions, in the experiment without processing for the same period, the decrease in grain moisture was 3.8%. Consequently, the proposed method of grain drying increases the efficiency of modern grain dryers.

Introduction. Enteral nutrition products (EP) are represented on the market by a wide range of imported products, the technology and formulations of which are unique and are objects of intellectual property of foreign scientific centers. The application of a unified methodological approach to the design of EP products will make it possible to transfer this process from an empirical to a scientifically based plane.

Purpose of research is to create a rational set of technological solutions for the production of specialized EP products based on the principles of modularity, taking into account the cascade of technological qualitative and quantitative transformations.

Materials and methods. Digital matrices of patient conditions, EP products and ingredients were used as materials. The main research method was advanced digital profiling, taking into account the transformation of nutrients in the production process.

Results. According to the formed matrices of the chemical composition of imported EP products, the criteria relationships of their digital profiles and state profiles were established. Based on the principles of food combinatorics and digital profiling, an algorithm for an improved approach to the design and production of EP is proposed. A generalized modular technology for the production of EP products has been developed and its variability has been proved without changing the structure due to the combinatorial versatility of each of the set of models. The degree of its available combinatorial variability has been established, which is functionally dependent on the number of combinatorially manipulated ingredients, taking into account all possible k-component compositions. The required set of formulations of EP products is a set of solutions in terms of design with the possibility of determining the vector of tasks to be solved.

Conclusions. The obtained research results can be applied in the food industry in terms of unified production of specialized products.

Introduction: For 14 years, interest in the use of dairy raw materials for the production of bioactive peptides (BPs) with antihypertensive, antioxidant and antidiabetic effects has been in a phase of rapid growth because of the need to prevent different diseases. Particular attention is being paid to enzymatic production method, as it allows for a targeted process of BP extraction with specified properties.

The  purpose of this scoping review was to summarize and systematize the experience of international research over the last 14 years in the field of FG as a method to extract BPs from milk protein substrates.

Materials and Methods: This scoping review was performed in accordance with the PRISMA-ScR guidelines. Scientific papers were searched in the Google Scholar database, because allows searching for scientific sources without restrictions on their format and type of scientific data presentation (book, dissertation, article), as well as includes scientific sources from other databases and performs relevance sorting.

Results:  The search identified 72 sources published between 2007 and 2021 in English. Included sources are devoted to hydrolysis by starter bacteria enzymes (SBE) - 50%  and by commercial enzyme preparations (CEP) - 50%.

Conclusion: There are a number of challenges that need to be addressed in order to increase the level of commercialization of BP production through directed hydrolysis. Creation of databases; building up the research base on co-fermentation by microorganisms and commercial enzymes; conducting PCR studies of microbial protease genes will increase the practical applicability of research and the validity of conducting more evidence-based in vivo and clinical studies.

Introduction: An important feature of microorganisms is the ability to adapt to adverse external influences, including the development of multiple antimicrobial resistance, leading to such negative consequences for humans as nosocomial infections, problems with cleaning rooms, medical and industrial equipment. The active use of chemical disinfectants for high-quality disinfection and cleaning has a number of disadvantages, including the risks of pathogens with new mechanisms of resistance to antimicrobial agents. The search for new, effective and safe antimicrobial agents as an alternative to chemical disinfectants is relevant. The use of probiotic strains of microorganisms, including lactic acid bacteria, in this capacity may be a promising area of research.

Objective: to analyze the literature data on studies of the potential of probiotic organisms, including lactic acid bacteria, to develop alternative disinfection and prevention strategies.

Materials and methods: This review of the subject field has been prepared based on the guiding principles of PRISMA-ScR. SCOPUS, Google Scholar, and RSCI databases were used. The works in Russian and English were considered, for the period 1995-2023.

Results: The review included 89 articles exploring the disadvantages of traditional disinfection methods and the search for alternative sanitation strategies. The description of various solutions for the introduction of probiotic purification methods is systematized – using bacteriophages, probiotic microorganisms of R. Bacillus and representatives of lactic acid bacteria as active agents.

Conclusions: A system of sanitary measures based on probiotic biodesinfectants, including lactic acid bacteria, can be included among the tools for countering pathogens, including their biofilms and forms with multidrug resistance. The introduction of a probiotic hygienic cleaning system, without having a negative impact on the environment, can increase the effectiveness of traditional hygienic preventive measures both in medical institutions and in production.