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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">foodmeta</journal-id><journal-title-group><journal-title xml:lang="ru">FOOD METAENGINEERING</journal-title><trans-title-group xml:lang="en"><trans-title>FOOD METAENGINEERING</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2949-6497</issn><publisher><publisher-name>All-Russian Dairy Research Institute</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37442/fme.2024.2.56</article-id><article-id custom-type="elpub" pub-id-type="custom">foodmeta-56</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Оригинальное эмпирическое исследование</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Original Empirical Research</subject></subj-group></article-categories><title-group><article-title>Изучение стимулирования роста бифидобактерий постбиотическим комплексом кисломолочного продукта как один из факторов повышения его биологической эффективности</article-title><trans-title-group xml:lang="en"><trans-title>The Role of Postbiotic Composition in the Growth Stimulating of Bifidobacteria</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9816-1720</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колоколова</surname><given-names>Анастасия Юрьевна</given-names></name><name name-style="western" xml:lang="en"><surname>Kolokolova</surname><given-names>Anastasia Yuryevna</given-names></name></name-alternatives><bio xml:lang="ru"><p>Старший научный сотрудник,  лаборатории прикладной микробиологии и геномики микроорганизмов</p></bio><email xlink:type="simple">a_kolokolova@vnimi.org</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-9498-4757</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кишилова</surname><given-names>Светлана Анатольевна</given-names></name><name name-style="western" xml:lang="en"><surname>Kishilova</surname><given-names>Svetlana Anatolyevna</given-names></name></name-alternatives><bio xml:lang="ru"><p>Младший научный сотрудник,  лаборатории прикладной микробиологии и геномики микроорганизмов</p></bio><email xlink:type="simple">s_kishilova@vnimi.org</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4441-4515</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рожкова</surname><given-names>Ирина Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Rozhkova</surname><given-names>Irina Vladimirovna</given-names></name></name-alternatives><bio xml:lang="ru"><p>Старший научный сотрудник,  лаборатории прикладной микробиологии и геномики микроорганизмов</p></bio><email xlink:type="simple">i_rozhkova@vnimi.org</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-6826-988X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Митрова</surname><given-names>Вера Анатольевна</given-names></name><name name-style="western" xml:lang="en"><surname>Mitrova</surname><given-names>Vera Anatolyevna</given-names></name></name-alternatives><bio xml:lang="ru"><p>Младший научный сотрудник,  лаборатории прикладной микробиологии и геномики микроорганизмов</p></bio><email xlink:type="simple">v_mitrova@vnimi.org</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Всероссийский научно-исследовательский институт молочной промышленности</institution><country>Россия</country></aff><aff xml:lang="en"><institution>All-Russian Dairy Research Institute</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>30</day><month>06</month><year>2024</year></pub-date><volume>2</volume><issue>2</issue><fpage>12</fpage><lpage>21</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Колоколова А.Ю., Кишилова С.А., Рожкова И.В., Митрова В.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Колоколова А.Ю., Кишилова С.А., Рожкова И.В., Митрова В.А.</copyright-holder><copyright-holder xml:lang="en">Kolokolova A.Y., Kishilova S.A., Rozhkova I.V., Mitrova V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.fme-journal.org/jour/article/view/56">https://www.fme-journal.org/jour/article/view/56</self-uri><abstract><sec><title>Введение</title><p>Введение: известно, что пробиотические микроорганизмы повышают питательную ценность пищевых продуктов, снижают уровень холестерина, положительно влияют на иммунную систему, предотвращают кишечные инфекции и диарею, связанную с антибиотиками, уменьшают симптомы непереносимости лактозы и др. Эти положительные эффекты зависят от свойств пробиотического штамма. Продукты метаболизма пробиотических микроорганизмов также способны оказывать положительное воздействие на организм человека. Метаболитные комплексы, секретируемые пробиотическими бактериями характеризуются высокой усвояемостью и устойчивостью к условиям окружающей среды и потенциально могут использоваться наряду с пробиотическими микроорганизмами.</p></sec><sec><title> </title><p> </p></sec><sec><title>Цель</title><p>Цель: Изучение. возможного влияния различных концентраций постбиотической композиции на усиление биологических свойств продукта, в частности, его   способности стимулировать рост бифидобактерий.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы: в качестве объектов исследования использовали кисломолочный продукт, на основе пробиотической ассоциации в составе Lactococcus cremoris 241Ц, Lactocaseibacillus rhamnosus F, Propionibacterium shermanii Э2, выработанный с применением постбиотического комплекса (ПК) в концентрациях 0,5 и 0,01%. При исследовании способности стимулировать рост бифидобактерий в качестве контрольной культуры использовали штамм Bifidobacterium adolescentis МС–42 из коллекции ФГАНУ «ВНИМИ». Исследования проводили на среде ГМК 2 и пробиотическом кисломолочном продукте, выработанном на стерильном обезжиренном молоке. Было изучено влияние двух концентраций ПК (0,5 и 0,01%), стимулировать рост бифидобактерий в экспериментальных образцах через 8 и 24 часа инкубирования.</p></sec><sec><title>Результаты</title><p>Результаты: Подтверждено положительное влияние ПК в концентрации 0,01% на рост бифидобактерий. Отсутствие стимулирующего действия ПК в концентрации 0,5% может быть связано с ингибированием уксусной кислотой - конечным продуктом метаболизма бифидобактерий, которая также входит в состав ПК. Об этом также косвенно свидетельствует и более низкое значение активной кислотности, которая, как известно, является определяющим фактором для роста бифидобактерий.</p></sec><sec><title>Выводы</title><p>Выводы: Полученные данные позволяют подтвердить увеличение биологической эффективности кисломолочного продукта с постбиотическим комплексом применительно к стимулированию роста бифидобактерий, и рекомендовать его в качестве добавки в биотехнологическую систему в концентрации 0,01%.</p></sec><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction: Probiotic microorganisms are known to increase the biological value of foods, reduce cholesterol levels, positively affect the immune system, prevent intestinal infections and diarrhea associated with antibiotics, reduce symptoms of lactose intolerance, etc. These positive effects depend on the properties of the probiotic strain. The metabolic products of probiotic microorganisms are also capable of having a positive effect on the human body. The metabolic complexes secreted by probiotic bacteria are characterized by high digestibility and resistance to environmental conditions and can potentially be used along with probiotic microorganisms.</p></sec><sec><title>Purpose</title><p>Purpose: To study. the possible effect of different concentrations of the postbiotic composition on enhancing the biological properties of the product, in particular, its ability to stimulate the growth of bifidobacteria.</p></sec><sec><title>Materials and Methods</title><p>Materials and Methods: As objects of research, a fermented milk product based on a probiotic association consisting of Lactococcus cremoris 241C, Lactocaseibacillus rhamnosus F, Propionibacterium shermanii E2, developed using a postbiotic complex (PC) in concentrations of 0.5 and 0.01%, was used. In the study of the ability to stimulate the growth of bifidobacteria, a strain of Bifidobacterium adolescentis MS–42 from the collection of FGANU «VNIMI» was used as a control culture. The studies were carried out on the GMC 2 medium and a probiotic fermented milk product developed on sterile skimmed milk. The effect of two PC concentrations (0.5 and 0.01%) on stimulating the growth of bifidobacteria in experimental samples after 8 and 24 hours of incubation was studied.</p></sec><sec><title>Results</title><p>Results: The positive effect of PC at a concentration of 0.01% on the growth of bifidobacteria was confirmed. The absence of a stimulating effect of PC in a concentration of 0.5% may be due to inhibition by acetic acid - the final product</p></sec><sec><title>Conclusion</title><p>Conclusion: The data obtained allow us to confirm the increase in the biological effectiveness of a fermented milk product with a postbiotic complex in relation to stimulating the growth of bifidobacteria, and recommend it as an additive to the biotechnological system at a concentration of 0.01%.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>пробиотик</kwd><kwd>постбиотический комплекс</kwd><kwd>ассоциация микроорганизмов</kwd><kwd>стимулирование роста бифидобактерий</kwd><kwd>кисломолочный продукт.</kwd></kwd-group><kwd-group xml:lang="en"><kwd>probiotic</kwd><kwd>postbiotic complex</kwd><kwd>association of microorganisms</kwd><kwd>stimulation of growth of bifidobacteria</kwd><kwd>fermented milk product</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">ФГАНУ "ВНИМИ"</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Агаркова, Е.Ю., Кручинин, А.Г., &amp; Рязанцева, К.А. 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