foodmetaFOOD METAENGINEERINGFOOD METAENGINEERING2949-6497All-Russian Dairy Research Institute10.37442/fme.2023.3.23foodmeta-23Research ArticleОбзорная статьяScoping ReviewПерспективы использования пробиотических организмов для разработки альтернативных стратегий дезинфекции и профилактикиProspects for the use of probiotic organisms to develop alternative strategies for disinfection and prevention of infectious diseaseshttps://orcid.org/0009-0000-9498-4757КишиловаСветлана АнатольевнаKishilovaSvetlana Anatolievna

младший научный сотрудник

junior researcher

s.a.kishilova@gmail.comВсероссийский НИИ молочной промышленностиРоссияAll-Russian Dairy Research InstituteRussian Federation202315122023136684Copyright © Кишилова С.А., 20232023Кишилова С.А.Kishilova S.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.fme-journal.org/jour/article/view/23Введение

Введение: Важной особенностью микроорганизмов является способность к адаптации к неблагоприятным внешним воздействиям, в том числе выработка множественной устойчивости к антимикробным препаратам, приводящая к таким негативным последствиям для человека, как внутрибольничные инфекции, проблемы с очисткой помещений, медицинского и промышленного оборудования. Активное применение химических дезинфицирующих средств для качественной дезинфекции и уборки имеет ряд недостатков, в том числе риски появления патогенов с новыми механизмами устойчивости к антимикробным агентам. Актуален поиск новых, эффективных и безопасных антимикробных агентов, в качестве альтернативы химическим дезинфицирующим средствам. Использование в этом качестве пробиотических штаммов микроорганизмов, в том числе молочнокислых бактерий, может являться перспективным направлением исследований.

Цель

Цель: проанализировать литературные данные, касающихся исследований потенциала пробиотических организмов, в том числе молочнокислых бактерий, для разработки альтернативных стратегий дезинфекции и профилактики.

Материалы и методы

Материалы и методы: Данный обзор предметного поля подготовлен исходя из руководящих приципов PRISMA-ScR. Использовались базы данных SCOPUS, Google Scholar, РИНЦ.  Рассматривались работы на русском и английском языках, за период 1995 - 2023 гг.

Результаты

Результаты: В обзор были включены 89 статей, исследующих проблему недостатков традиционных методов дезинфекции и поиска альтернативных стратегий санитарии. Систематизировано описание различных решений для внедрения методов пробиотической очистки – с использованием в качестве действующих агентов бактериофагов, пробиотических микроорганизмов р. Bacillus и представителей молочнокислых бактерий.

Выводы

Выводы: Система санитарных мероприятий на основе пробиотиков - биодезинфектантов, в том числе молочнокислых бактерий, может быть включена в число инструментов противодействия патогенам, включая их биопленки и формы с множественной лекарственной устойчивостью. Внедрение пробиотической гигиенической системы очистки, не оказывая негативного влияния на окружающую среду, способно повышать эффективность традиционных гигиенических профилактических мероприятий как в лечебных учреждениях, так и на производствах.

Introduction

Introduction: An important feature of microorganisms is the ability to adapt to adverse external influences, including the development of multiple antimicrobial resistance, leading to such negative consequences for humans as nosocomial infections, problems with cleaning rooms, medical and industrial equipment. The active use of chemical disinfectants for high-quality disinfection and cleaning has a number of disadvantages, including the risks of pathogens with new mechanisms of resistance to antimicrobial agents. The search for new, effective and safe antimicrobial agents as an alternative to chemical disinfectants is relevant. The use of probiotic strains of microorganisms, including lactic acid bacteria, in this capacity may be a promising area of research.

Objective

Objective: to analyze the literature data on studies of the potential of probiotic organisms, including lactic acid bacteria, to develop alternative disinfection and prevention strategies.

Materials and methods

Materials and methods: This review of the subject field has been prepared based on the guiding principles of PRISMA-ScR. SCOPUS, Google Scholar, and RSCI databases were used. The works in Russian and English were considered, for the period 1995-2023.

Results

Results: The review included 89 articles exploring the disadvantages of traditional disinfection methods and the search for alternative sanitation strategies. The description of various solutions for the introduction of probiotic purification methods is systematized – using bacteriophages, probiotic microorganisms of R. Bacillus and representatives of lactic acid bacteria as active agents.

Conclusions

Conclusions: A system of sanitary measures based on probiotic biodesinfectants, including lactic acid bacteria, can be included among the tools for countering pathogens, including their biofilms and forms with multidrug resistance. The introduction of a probiotic hygienic cleaning system, without having a negative impact on the environment, can increase the effectiveness of traditional hygienic preventive measures both in medical institutions and in production.

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The authors declare that there are no conflicts of interest present.